翻訳と辞書 Words near each other ・ Trans-2,3-Butylene carbonate ・ Trans-2,3-dihydro-3-hydroxyanthranilate isomerase ・ Trans-2-decenoyl-(acyl-carrier protein) isomerase ・ Trans-2-enoyl-CoA reductase (NAD+) ・ Trans-2-enoyl-CoA reductase (NADPH) ・ Trans-2-Methyl-2-butenal ・ Trans-2-Phenyl-1-cyclohexanol ・ Trans-3-Methyl-2-hexenoic acid ・ Trans-3-Methyl-4-decanolide ・ Trans-3-Methyl-4-octanolide ・ Trans-4,5-Epoxy-(E)-2-decenal ・ Trans-acenaphthene-1,2-diol dehydrogenase ・ Trans-aconitate 2-methyltransferase ・ Trans-aconitate 3-methyltransferase ・ Trans-acting ・ Trans-acting siRNA ・ Trans-activating crRNA ・ Trans-activation response element (TAR) ・ Trans-Afghanistan Pipeline ・ Trans-African Highway network ・ Trans-Alaska Pipeline Authorization Act ・ Trans-Alaska Pipeline System ・ Trans-Alay Range ・ Trans-Allegheny Lunatic Asylum ・ Trans-Am Production Cars ・ Trans-Am Series ・ Trans-Amazonian Highway ・ Trans-Amazonian Railway ・ Trans-American Footrace ・ Trans-Anatolian gas pipeline Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Trans-acting siRNA ： ウィキペディア英語版 Trans-acting siRNA ''Trans''-acting siRNA (abbreviated "TAS", "ta-siRNA" or sometimes "tasiRNA") is a form of small interfering RNA (siRNA) that represses gene expression through post-transcriptional gene silencing in land plants. Ta-siRNAs are transcribed from the genome to form a polyadenylated, double-stranded segment of RNA that gets processed further, resulting in a segment of RNA that is 21-nucleotides long.〔 These segments are incorporated into the RNA-induced Silencing Complex (RISC) and direct the cleavage of target mRNA. ta-siRNAs are termed siRNA because they undergo similar processing and both arise from double-stranded RNA (dsRNA). However, ta-siRNAs differ from other siRNAs in that they bind with less sequence specificity to their targets.〔 They function more like microRNAs because they do not require full sequence complementarity in order to direct cleavage of the target RNA. == Discovery == The presence of ta-siRNAs was originally detected in 2004 by two different lab groups researching the flowering plant arabidopsis. Both papers were published in October within days of each other. One lab group (Peragine et al.) was investigating the Argonaute protein ZIPPY (ZIP), and the other (Vazquez et al.) was trying to identify a specific small interfering RNA (siRNA) pathway.〔〔 Despite starting at different points, both research groups found their projects involving the plant specific protein, suppressor of gene silencing 3 (SGS3), and the enzyme RNA-dependant RNA polymerase 6 (RDR6). Both groups found that SGS3 and RDR6 are important in the generation of a specific group of small RNAs (sRNAs) termed ta-siRNAs.〔〔 Because of key differences that set them apart from other sRNAs, Ta-siRNAs were a new discovery despite sharing similarities with both siRNAs and microRNAs (miRNAs). Unlike miRNAs, it was found that ta-siRNAs are derived from long double-stranded RNA (dsRNA), and their generation is RDR6 dependant.〔 Ta-siRNAs differ from siRNAs because they direct cleavage of transcripts which are not identical. In this way ta-siRNAs are more functionally similar to miRNAs, but are produced in the same manner as siRNAs.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Trans-acting siRNA」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.